The activation of EphA2 changes the expression of E-cadherin and reduces cell-cell or cell-matrix adhesion (Zantek et al., 1999), and the upregulation or downregulation of E-cadherin can also alter the manifestation of Eph receptors or ephrin ligands (Orsulic and Kemler, 2000). with modified N-cadherin adhesion junctions (Cheng and Gong, 2011; Jun et al., 2009) as… Continue reading The activation of EphA2 changes the expression of E-cadherin and reduces cell-cell or cell-matrix adhesion (Zantek et al