In case of p53 DBD Nb105, co-treatment with SAHA led to a 7

In case of p53 DBD Nb105, co-treatment with SAHA led to a 7.17-fold reduction of p53 levels. strongly nuclear enriched, its tumour suppressive functions were hampered. We argue that the absence of a tumour suppressive effect is caused by inhibition of p53 transactivation in both HPV-infected and HPV-negative cells. The inactivation of the transcriptional activity… Continue reading In case of p53 DBD Nb105, co-treatment with SAHA led to a 7