Nevertheless, the impact of HIPK1 on PAGE4 function is largely cell type-specific, namely enhancing PAGE4 protection on ROS in LNCaP cells that express functional AR but attenuating PAGE4 function in DU145 cells, in which AR is silenced. male worldwide. Oxidative stress has been recognized as one of the driving signals pathologically linked to PCa progression.… Continue reading Nevertheless, the impact of HIPK1 on PAGE4 function is largely cell type-specific, namely enhancing PAGE4 protection on ROS in LNCaP cells that express functional AR but attenuating PAGE4 function in DU145 cells, in which AR is silenced